For over seven decades, Semo Pest has proudly served the St. Louis and St. Charles metropolitan areas from our headquarters in New Melle, Missouri. As a locally owned and operated family business, we’re deeply committed to protecting homes and businesses from unwanted invaders by providing reliable, efficient, and environmentally responsible pest control solutions. Our state-certified technicians bring decades of experience to every job, tailoring treatment plans to your specific needs and delivering exceptional service with a personal touch.

Whether you’re facing termites, bed bugs, or other persistent pests, Semo Pest offers flexible coverage designed to bring you peace of mind. We believe in doing right by our customers and the community, ensuring that every home and commercial property receives the attentive care it deserves. With us, you’re more than a service call; you’re part of our legacy of trust, safety, and excellence.